anti- NFKBIZ antibody

Product Description

anti- NFKBIZ antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis(By similarity)..

Immunogen: nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

Synonyms: IKBZ, INAP, MAIL

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05709(NFKBIZ antibody) at dilution of 1:600

Gene ID: 64332

Research Area: Metabolism

Uniprot ID: Q9BYH8