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Product Description
anti- NMRAL1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Redox sensor protein. Undergoes restructuring and subcellular redistribution in response to changes in intracellular NADPH/NADP(+) levels. At low NADPH concentrations the protein is found mainly as a monomer, and binds argininosuccinate synthase(ASS1), the enzyme involved in nitric oxide synthesis. Association with ASS1 impairs its activity and reduces the production of nitric oxide, which subsecuently prevents apoptosis. Under normal NADPH concentrations, the protein is found as a dimer and hides the binding site for ASS1. The homodimer binds one molecule of NADPH. Has higher affinity for NADPH than for NADP(+). Binding to NADPH is necessary to form a stable dimer..
Immunogen: NmrA-like family domain containing 1
Synonyms: HSCARG
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human liver using FNab05769(NMRAL1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05769(NMRAL1 antibody) at dilution of 1:500
Gene ID: 57407
Research Area: Metabolism
Uniprot ID: Q9HBL8
