anti- NOX4 antibody

Product Description

anti- NOX4 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation..

Immunogen: NADPH oxidase 4

Synonyms: Kidney oxidase 1, KOX, KOX 1, NADPH oxidase 4, NOX4, Renal NAD(P)H oxidase, RENOX

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP, IF, FC

Recommended dilution: WB: 1:200-1:2000; IP: 1:500-1:2000; IHC: 1:100-1:400; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab05806(NOX4 Antibody) at dilution of 1:200

Image 2: Immunofluorescent analysis of BxPC-3 cells using FNab05806 (NOX4 antibody) at dilution of 1:25 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05806(NOX4 antibody) at dilution of 1:600

Gene ID: 50507

Research Area: Metabolism

Uniprot ID: Q9NPH5