anti- NR1H3 antibody

Product Description

anti- NR1H3 antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Nuclear receptor. Interaction with RXR shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES. LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides. Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8. Interplays functionally with RORA for the regulation of genes involved in liver metabolism(By similarity). Exhibits a ligand-dependent transcriptional activation activity(PubMed:25661920)..

Immunogen: nuclear receptor subfamily 1, group H, member 3

Synonyms: Liver X receptor alpha, LXR a, LXRA, NR1H3, Oxysterols receptor LXR alpha, RLD 1

Reactivity: Human, Rat

Tested Application: ELISA, WB, IF

Recommended dilution: WB: 1:200-1:1000; IF: 1:10-1:100

Image 1:

Image 2: Immunofluorescent analysis of HepG2 cells using FNab05836( NR1H3 Antibody) at dilution of 1:25 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L).

Image 3:

Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab05836(NR1H3 antibody) at dilution of 1:500

Gene ID: 10062

Research Area: Metabolism

Uniprot ID: Q13133