anti- NT5E/CD73 antibody

Product Description

anti- NT5E/CD73 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: NT5E(5'-nucleotidase) is also named as NT5, NTE,CD73,ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling(PMID:17619139). This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer(PMID:17619139). It can be detected the band of 55 kDa,64 kDa, 70 kDa, 110 kDa by western blot(PMID:17619139; 12370277; 21533188). Defects in NT5E are the cause of calcification of joints and arteries(CALJA)..

Immunogen: 5'-nucleotidase, ecto(CD73)

Synonyms: 5 NT, 5 nucleotidase, 5' nucleotidase, ecto(CD73), CD73, E5NT, Ecto 5 nucleotidase, eN, eNT, NT, NT5, NT5E, NTE

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB,IHC,FC

Recommended dilution: WB: 1:500-1:5000; IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human stomach cancer tissue slide using FNab05878(NT5E,CD73 Antibody) at dilution of 1:200

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab05878(NT5E,CD73 antibody) at dilution of 1:1000

Gene ID: 4907

Research Area: Metabolism

Uniprot ID: P21589