Product Description
anti- OPRL1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins(G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin..
Immunogen: opiate receptor-like 1
Synonyms: OOR, ORL1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human gliomas using FNab05997(OPRL1 antibody) at dilution of 1:100
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab05997(OPRL1 antibody) at dilution of 1:500
Gene ID: 4987
Research Area: Metabolism
Uniprot ID: P41146