anti- P16-INK4A antibody

Product Description

anti- P16-INK4A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: CDKN2A generates several transcript variants which differ in their first exons. At least three alternatively-spliced variants encoding distinct proteins have been reported, and two are related, named p16-INK4 and p14 respetively, sharing 50% identity. The third one is completely stuctually un-related, called p14(ARF) or p19(ARF). FNab06064 reacted with p16 specifically. P16 plays an important role in regulating the cell cycle, and mutations in p16 increase the risk of developing a variety of cancers, notably melanoma..

Immunogen: cyclin-dependent kinase inhibitor 2A(melanoma, p16, inhibits CDK4)

Synonyms: ARF,CDKN2A, CDK4 inhibitor p16 INK4, CDK4 inhibitor p16INK4, CDK4I, CDKN2, CDKN2A, CMM2, INK4, INK4a, MLM, MTS 1, MTS1, Multiple tumor suppressor 1, p14, p14ARF, P16, p16 INK4, p16 INK4a, p16INK4, p16INK4a, P19, TP16

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF, IP, IHC, FC

Recommended dilution: WB: 1:500-1:5000; IP: 1:500-1:5000; IHC: 1:50-1:500; IF: 1:20-1:200

Image 1: Immunohistochemistry of paraffin-embedded human tonsillitis tissue slide using FNab06064(P16-INK4A Antibody) at dilution of 1:200 heat mediated antigen retrieved with Tris-EDTA buffer(pH9).

Image 2: .

Image 3: IP Result of anti-P16 (IP: FNab06064, 4ug; Detection: FNab06064 1:1000) with HEK-293 cells lysate 4500ug.

Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06064(P16 antibody) at dilution of 1:1000

Gene ID: 1029

Research Area: Metabolism

Uniprot ID: P42771