anti- PACSIN1 antibody

Product Description

anti- PACSIN1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Plays a role in the reorganization of the microtubule cytoskeleton via its interaction with MAPT; this decreases microtubule stability and inhibits MAPT-induced microtubule polymerization. Plays a role in cellular transport processes by recruiting DNM1, DNM2 and DNM3 to membranes. Plays a role in the reorganization of the actin cytoskeleton and in neuron morphogenesis via its interaction with COBL and WASL, and by recruiting COBL to the cell cortex. Plays a role in the regulation of neurite formation, neurite branching and the regulation of neurite length. Required for normal synaptic vesicle endocytosis; this process retrieves previously released neurotransmitters to accommodate multiple cycles of neurotransmission. Required for normal excitatory and inhibitory synaptic transmission(By similarity). Binds to membranes via its F-BAR domain and mediates membrane tubulation..

Immunogen: protein kinase C and casein kinase substrate in neurons 1

Synonyms: KIAA1379

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IF

Recommended dilution:

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Image 4: mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab06100( PACSIN1 Antibody) at dilution of 1:1000

Gene ID: 29993

Research Area: Metabolism

Uniprot ID: Q9BY11