anti- PASK antibody

Product Description

anti- PASK antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions(oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: regulates glycogen synthase synthesis by mediating phosphorylation of GYS1, leading to GYS1 inactivation. May be involved in glucose-stimulated insulin production in pancreas and regulation of glucagon secretion by glucose in alpha cells; however such data require additional evidences. May play a role in regulation of protein translation by phosphorylating EEF1A1, leading to increase translation efficiency. May also participate to respiratory regulation..

Immunogen: PAS domain containing serine/threonine kinase

Synonyms: KIAA0135

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human testis tissue slide using FNab06165(PASK Antibody) at dilution of 1:50

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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab06165(PASK antibody) at dilution of 1:1000

Gene ID: 23178

Research Area: Metabolism

Uniprot ID: Q96RG2