Product Description
anti- PDCD4 antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA(By similarity)..
Immunogen: programmed cell death 4(neoplastic transformation inhibitor)
Synonyms: H731, Nuclear antigen H731 like, PDCD4, Protein 197/15a
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution: WB: 1:1000-1:4000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab06240(PDCD4 Antibody) at dilution of 1:50
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06240(PDCD4 Antibody) at dilution of 1:2000
Gene ID: 27250
Research Area: Metabolism
Uniprot ID: Q53EL6