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Product Description
anti- PDK1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Plays an important role in cellular responses to hypoxia and is important for cell proliferation under hypoxia. Protects cells against apoptosis in response to hypoxia and oxidative stress..
Immunogen: pyruvate dehydrogenase kinase, isozyme 1
Synonyms: PDHK1
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human liver using FNab06276(PDK1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab06276(PDK1 Antibody) at dilution of 1:2000
Gene ID: 5163
Research Area: Metabolism
Uniprot ID: Q15118
