anti- PDZK1 antibody

Product Description

anti- PDZK1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene..

Immunogen: PDZ domain containing 1

Synonyms: CAP70, NHERF3, PDZD1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:20 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human liver tissue slide using FNab06298(PDZK1 antibody) at dilution of 1:50

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Image 4: mouse liver tissue were subjected to SDS PAGE followed by western blot with FNab06298(PDZK1 antibody) at dilution of 1:1000

Gene ID: 5174

Research Area: Metabolism

Uniprot ID: Q5T2W1