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Product Description
anti- PELI2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS-and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP(mitogen activated protein) kinase pathway leading to activation of ELK1..
Immunogen: pellino homolog 2(Drosophila)
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IF
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human ovary tissue slide using FNab06304(PELI2 Antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab06304(PELI2 Antibody) at dilution of 1:600
Gene ID: 57161
Research Area: Metabolism
Uniprot ID: Q9HAT8
