anti- PEX5 antibody

Product Description

anti- PEX5 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The product of this gene binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of neonatal adrenoleukodystrophy (NALD), a cause of Zellweger syndrome (ZWS) as well as may be a cause of infantile Refsum disease (IRD). Alternatively spliced transcript variants encoding different isoforms have been identified..

Immunogen: peroxisomal biogenesis factor 5

Synonyms: FLJ50634, FLJ50721, FLJ51948, Peroxin 5, Peroxisome receptor 1, PEX5, PTS1 BP, PTS1 receptor, PTS1R, PXR1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded mouse kidney tissue slide using FNab06331( PEX5 Antibody) at dilution of 1:100

Image 2: Immunofluorescence analysis of HeLa cells using FNab06331( PEX5 Antibody). Blue: DAPI for nuclear staining..

Image 3:

Image 4: SW480 cells were subjected to SDS PAGE followed by western blot with FNab06331(PEX5 antibody) at dilution of 1:1000

Gene ID: 5830

Research Area: Metabolism

Uniprot ID: P50542