Product Description
anti- Phospho-Akt(Ser473) antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: The serine-threonine protein kinase AKT1 is catalytically inactive in serum-starved primary and immortalized fibroblasts. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. This antibody detects all the members of AKT with phospho-modification..
Immunogen: v-akt murine thymoma viral oncogene homolog 1
Synonyms: AKT, AKT1, AKT1-phospho-S473, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, IHC, WB
Recommended dilution: WB: 1:1000-1:4000; IHC: 1:50-1:200
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab06402(Phospho-Akt (S473) Antibody) at dilution of 1:200
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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06402(Phospho-Akt (S473) Antibody) at dilution of 1:2000
Research Area: Metabolism
Uniprot ID: P31749