anti- PI3K p85(alpha) antibody

Product Description

anti- PI3K p85(alpha) antibody is available at Gentaur for Next week Delivery.

Purification: Protein A+G purification

Background: Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome..

Immunogen: phosphoinositide-3-kinase, regulatory subunit 1(alpha)

Synonyms: GRB1, p85, p85 ALPHA, PI 3 Kinase p85 alpha, PI 3-kinase p85?, PI3 kinase subunit p85 alpha, PI3K p85(alpha), PI3K regulatory subunit alpha, PIK3R1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF, IP

Recommended dilution: WB: 1:1000-1:10000; IP: 1:200-1:2000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer slide using FNab06422(PIK3R1 Antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of (-20? Ethanol ) fixed HeLa cells using FNab06422(PIK3R1 Antibody) at dilution of 1:100 and Alexa Fluor 488-conjugated Goat Anti-Mouse IgG(H+L).

Image 3: IP Result of anti- PIK3R1 (IP: FNab06422, 5ug; Detection: FNab06422 1:500) with RAW 264.7 cells lysate 1480ug.

Image 4: Neuro-2a cells were subjected to SDS PAGE followed by western blot with FNab06422(PIK3R1 Antibody) at dilution of 1:4000

Gene ID: 5295

Research Area: Metabolism

Uniprot ID: P27986