anti- PICK1 antibody

Product Description

anti- PICK1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor(AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression(LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function..

Immunogen: protein interacting with PRKCA 1

Synonyms: PRKCABP

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, WB, IP, IF

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human prostate cancer using FNab06434(PICK1 antibody) at dilution of 1:50

Image 2: .

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06434(PICK1 antibody) at dilution of 1:500

Gene ID: 9463

Research Area: Metabolism

Uniprot ID: Q9NRD5