anti- PIK3C2A antibody

Product Description

anti- PIK3C2A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to nanomolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling..

Immunogen: phosphoinositide-3-kinase, class 2, alpha polypeptide

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:100 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat heart using FNab06449(PIK3C2A antibody) at dilution of 1:100

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Image 4: PC-3 cells were subjected to SDS PAGE followed by western blot with FNab06449(PIK3C2A antibody) at dilution of 1:1500

Gene ID: 5286

Research Area: Metabolism

Uniprot ID: O00443