anti- PKC alpha antibody

Product Description

anti- PKC alpha antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been reported to play roles in many different cellular processes, such as cell adhesion, cell transformation, cell cycle checkpoint, and cell volume control. Knockout studies in mice suggest that this kinase may be a fundamental regulator of cardiac contractility and Ca(2+) handling in myocytes..

Immunogen: protein kinase C, alpha

Synonyms: AAG6, PKC A, PKC alpha, PKCA, PRKACA, PRKCA, Protein kinase C alpha type, protein kinase C, alpha

Reactivity: Human

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human thyroid cancer tissue slide using FNab06480( PRKCA Antibody) at dilution of 1:200

Image 2: Immunofluorescent analysis of ( -20? Ethanol ) fixed HeLa cells using FNab06480( PRKCA Antibody) at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab06480(PRKCA antibody) at dilution of 1:1000

Gene ID: 5578

Research Area: Metabolism

Uniprot ID: P17252