anti- PKC beta antibody

Product Description

anti- PKC beta antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported..

Immunogen: protein kinase C, beta

Synonyms: PKC B, PKC beta, PKCB, PRKCB, PRKCB1, PRKCB2, Protein kinase C beta type, protein kinase C, beta

Reactivity: Mouse

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06481(PRKCB antibody) at dilution of 1:50

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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab06481(PRKCB antibody) at dilution of 1:1000

Gene ID: 5579

Research Area: Metabolism

Uniprot ID: P05771