anti- PKC epsilon antibody

Product Description

anti- PKC epsilon antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior..

Immunogen: protein kinase C, epsilon

Synonyms: PKCE, nPKC-epsilon

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, ICC

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; ICC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat spleen using FNab06484 (PKC epsilon antibody) at dilution of 1:200

Image 2: .

Image 3:

Image 4: mouse lung tissue were subjected to SDS PAGE followed by western blot with FNab06484 (PKC epsilon antibody) at dilution of 1:1000

Gene ID: 5581

Research Area: Metabolism

Uniprot ID: Q02156