Product Description
anti- PKC iota antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Calcium-and diacylglycerol-independent serine/ threonine-protein kinase that plays a general protective role against apoptotic stimuli, is involved in NF-kappa-B activation, cell survival, differentiation and polarity, and contributes to the regulation of microtubule dynamics in the early secretory pathway. Is necessary for BCR-ABL oncogene-mediated resistance to apoptotic drug in leukemia cells, protecting leukemia cells against drug-induced apoptosis..
Immunogen: protein kinase C, iota
Synonyms: aPKC lambda/iota, DXS1179E, PKC iota, PKCI, PRKC lambda/iota, PRKCI, Protein kinase C iota type, protein kinase C, iota
Reactivity: Human
Tested Application: ELISA, IHC, WB, IP
Recommended dilution: WB: 1:500-1:1000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
Image 1: Immunohistochemistry of paraffin-embedded human lung cancer tissue slide using FNab06486(PRKCI Antibody) at dilution of 1:200
Image 2: Immunofluorescent analysis of ( 10% Formaldehyde ) fixed HeLa cells using FNab06486 (PKC iota antibody) at dilution of 1:50 and Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L).
Image 3: IP Result of anti-PKC iota (IP: FNab06486, 3ug; Detection: FNab06486 1:500) with HeLa cells lysate 2500ug.
Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06486(PRKCI antibody) at dilution of 1:500
Research Area: Metabolism
Uniprot ID: P41743