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Product Description
anti- PKM antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate(PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival..
Immunogen: PKM2 pyruvate kinase, muscle
Synonyms: OIP3, PK2, PK3, PKM2
Reactivity: Human, Mouse
Tested Application: ELISA, IHC, WB
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab06492(PKM antibody) at dilution of 1:50
Image 2: .
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Image 4: HepG2 cells were subjected to SDS PAGE followed by western blot with FNab06493(PKM antibody) at dilution of 1:1000
Gene ID: 5315
Research Area: Metabolism
Uniprot ID: P14618
