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Product Description
anti- PLAG1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Transcription factor whose activation results in up-regulation of target genes, such as IGFII, leading to uncontrolled cell proliferation: when overexpressed in cultured cells, higher proliferation rate and transformation are observed. Other target genes such as CRLF1, CRABP2, CRIP2, PIGF are strongly induced in cells with PLAG1 induction. Proto-oncogene whose ectopic expression can trigger the development of pleomorphic adenomas of the salivary gland and lipoblastomas. Overexpression is associated with up-regulation of IGFII, is frequently observed in hepatoblastoma, common primary liver tumor in childhood. Cooperates with CBFB-MYH11, a fusion gene important for myeloid leukemia..
Immunogen: pleiomorphic adenoma gene 1
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: A431 cells were subjected to SDS PAGE followed by western blot with FNab06515( PLAG1 Antibody) at dilution of 1:300
Gene ID: 5324
Research Area: Metabolism
Uniprot ID: Q6DJT9
