anti- PLEKHO1 antibody

Product Description

anti- PLEKHO1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein(CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2(CK2). Appears to target ATM to the plasma membrane. Appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity(plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation..

Immunogen: pleckstrin homology domain containing, family O member 1

Synonyms: CKIP1, OC120

Reactivity: Human, Mouse

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab06543(PLEKHO1 antibody) at dilution of 1:300

Gene ID: 51177

Research Area: Metabolism

Uniprot ID: Q53GL0