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Product Description
anti- POLI antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Error-prone DNA polymerase specifically involved in DNA repair. Plays an important role in translesion synthesis, where the normal high-fidelity DNA polymerases cannot proceed and DNA synthesis stalls. Favors Hoogsteen base-pairing in the active site. Inserts the correct base with high-fidelity opposite an adenosine template. Exhibits low fidelity and efficiency opposite a thymidine template, where it will preferentially insert guanosine. May play a role in hypermutation of immunogobulin genes. Forms a Schiff base with 5'-deoxyribose phosphate at abasic sites, but may not have lyase activity..
Immunogen: polymerase(DNA directed) iota
Synonyms: RAD30B
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab06612(POLI antibody) at dilution of 1:100
Image 2: .
Image 3:
Image 4: mouse testis tissue were subjected to SDS PAGE followed by western blot with FNab06612(POLI antibody) at dilution of 1:800
Gene ID: 11201
Research Area: Metabolism
Uniprot ID: Q9UNA4
