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Product Description
anti- POLR3D antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity)..
Immunogen: polymerase(RNA) III(DNA directed) polypeptide D, 44kDa
Synonyms: BN51, BN51T
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab06631(POLR3D antibody) at dilution of 1:1000
Gene ID: 661
Research Area: Metabolism
Uniprot ID: P05423
