anti- POLR3K antibody

Product Description

anti- POLR3K antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs(EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway(By similarity)..

Immunogen: polymerase(RNA) III(DNA directed) polypeptide K, 12.3 kDa

Synonyms: C11, C11 RNP3, hRPC11, HsC11p, My010, POLR3K, RNA polymerase III subunit C10, RNA polymerase III subunit C11, RPC10, RPC11, RPC12.5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, IHC, IF, WB

Recommended dilution: WB: 1:500-1:5000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human gliomas using FNab06634(POLR3K antibody) at dilution of 1:100

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Image 4: Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06634(POLR3K Antibody) at dilution of 1:1000

Gene ID: 51728

Research Area: Metabolism

Uniprot ID: Q9Y2Y1