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Product Description
anti- PPARA antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Ligand-activated transcription factor. Key regulator of lipid metabolism. Activated by the endogenous ligand 1-palmitoyl-2-oleoyl-sn-glycerol-3-phosphocholine(16:0/18:1-GPC). Activated by oleylethanolamide, a naturally occurring lipid that regulates satiety. Receptor for peroxisome proliferators such as hypolipidemic drugs and fatty acids. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the ACOX1 and P450 genes. Transactivation activity requires heterodimerization with RXRA and is antagonized by NR2C2. May be required for the propagation of clock information to metabolic pathways regulated by PER2..
Immunogen: peroxisome proliferator-activated receptor alpha
Synonyms: hPPAR, NR1C1, PPAR, PPAR alpha, PPARA
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC,IP
Recommended dilution: WB: 1:200-1:1000; IP: 1:200-1:1000 ; IHC: 1:50-1:200
Image 1: Immunohistochemistry of paraffin-embedded human skeletal muscle tissue slide using FNab06663(PPARA Antibody) at dilution of 1:100
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Image 4: U-937 cells were subjected to SDS PAGE followed by western blot with FNab06663(PPARA antibody) at dilution of 1:300
Gene ID: 5465
Research Area: Metabolism
Uniprot ID: Q07869
