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Product Description
anti- PRC1 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression(PubMed:17409436)..
Immunogen: protein regulator of cytokinesis 1
Synonyms:
Reactivity: Human
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab06749(PRC1 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: HEK-293T cells were subjected to SDS PAGE followed by western blot with FNab06749(PRC1 Antibody) at dilution of 1:600
Gene ID: 9055
Research Area: Metabolism
Uniprot ID: O43663
