anti- PSMB10 antibody

Product Description

anti- PSMB10 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome..

Immunogen: proteasome (prosome, macropain) subunit, beta type, 10

Synonyms: LMP10, MECL1

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse brain using FNab06869(PSMB10 antibody) at dilution of 1:50

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Image 4: human liver tissue were subjected to SDS PAGE followed by western blot with FNab06869(PSMB10 antibody) at dilution of 1:1000

Gene ID: 5699

Research Area: Metabolism

Uniprot ID: P40306