anti- PTPN11 antibody

Product Description

anti- PTPN11 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia..

Immunogen: protein tyrosine phosphatase, non-receptor type 11

Synonyms: PTP2C, SHPTP2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded rat heart using FNab06932( PTPN11 Antibody) at dilution of 1:100

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab06932( PTPN11 Antibody) at dilution of 1:1000

Gene ID: 5781

Research Area: Metabolism

Uniprot ID: Q06124