Product Description
anti- Rab23 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Together with SUFU, prevents nuclear import of GLI1, and thereby inhibits GLI1 transcription factor activity. Regulates GLI1 in differentiating chondrocytes. Likewise, regulates GLI3 proteolytic processing and modulates GLI2 and GLI3 transcription factor activity. Plays a role in autophagic vacuole assembly, and mediates defense against pathogens, such as S.aureus, by promoting their capture by autophagosomes that then merge with lysosomes..
Immunogen: RAB23, member RAS oncogene family
Synonyms:
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human liver cancer tissue slide using FNab07006(RAB23 Antibody) at dilution of 1:200
Image 2: .
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Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07006(RAB23 antibody) at dilution of 1:1000
Gene ID: 51715
Research Area: Metabolism
Uniprot ID: Q9ULC3