anti- RAD23A antibody

Product Description

anti- RAD23A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair(GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. Involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages. Required for the association of HIV-1 vpr with the host proteasome..

Immunogen: RAD23 homolog A(S. cerevisiae)

Synonyms:

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IP

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human lymphoma using FNab07077(RAD23A antibody) at dilution of 1:50

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Image 4: Jurkat cells were subjected to SDS PAGE followed by western blot with FNab07077(RAD23A antibody) at dilution of 1:500

Gene ID: 5886

Research Area: Metabolism

Uniprot ID: P54725