anti- RAD51 antibody

Product Description

anti- RAD51 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange(PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3..

Immunogen: RAD51 homolog

Synonyms: RAD51A, RECA

Reactivity: Human

Tested Application: ELISA, IHC

Recommended dilution: IHC: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human ovary cancer tissue slide using FNab10134(RAD51 Antibody) at dilution of 1:200

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Gene ID: 5888

Research Area: Metabolism

Uniprot ID: Q06609