Product Description
anti- Rad51D antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Involved in the homologous recombination repair(HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents. Bind to single-stranded DNA(ssDNA) and has DNA-dependent ATPase activity. Part of the Rad21 paralog protein complex BCDX2 which acts in the BRCA1-BRCA2-dependent HR pathway. Upon DNA damage, BCDX2 acts downstream of BRCA2 recruitment and upstream of RAD51 recruitment. BCDX2 binds predominantly to the intersection of the four duplex arms of the Holliday junction and to junction of replication forks. The BCDX2 complex was originally reported to bind single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Involved in telomere maintenance. The BCDX2 subcomplex XRCC2:RAD51D can stimulate Holliday junction resolution by BLM..
Immunogen: RAD51-like 3(S. cerevisiae)
Synonyms: RAD51L3
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human lymphoma using FNab07081(Rad51D antibody) at dilution of 1:100
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Image 4: COLO 320 cells were subjected to SDS PAGE followed by western blot with FNab07081(Rad51D antibody) at dilution of 1:1000
Gene ID: 5892
Research Area: Metabolism
Uniprot ID: O75771