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Product Description
anti- RAIDD antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: RAIDD, also named as CRADD, is an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex. CRADD interacts with BCL10 through its caspase recruitment domain and suppresses interactions between BCL10 and CARMA1. It is a negative regulator of the CARMA1 signalosome and suppressor of Th1-and Th17-mediated inflammatory responses..
Immunogen: CASP2 and RIPK1 domain containing adaptor with death domain
Synonyms: CRADD, RAIDD
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP
Recommended dilution: WB: 1:500-1:2000; IP: 1:500-1:2000; IHC: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human colon cancer using FNab07092(CRADD antibody) at dilution of 1:100
Image 2: .
Image 3: IP Result of anti-RAIDD (IP: FNab07092, 3ug; Detection:1 FNab07092 1:1000) with mouse kidney tissue lysate 4000ug.
Image 4: K-562 cells were subjected to SDS PAGE followed by western blot with FNab07092(CRADD antibody) at dilution of 1:1000
Research Area: Metabolism
Uniprot ID: P78560
