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Product Description
anti- RPL13A antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Associated with ribosomes but is not required for canonical ribosome function and has extra-ribosomal functions. Component of the GAIT(gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma activation and subsequent phosphorylation dissociates from the ribosome and assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs(such as ceruplasmin) and suppresses their translation. In the GAIT complex interacts with m7G cap-bound eIF4G at or near the eIF3-binding site and blocks the recruitment of the 43S ribosomal complex. Involved in methylation of rRNA..
Immunogen: ribosomal protein L13a
Synonyms:
Reactivity: Human, Mouse
Tested Application: ELISA, WB
Recommended dilution:
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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07413(RPL13A antibody) at dilution of 1:400
Gene ID: 23521
Research Area: Metabolism
Uniprot ID: P40429
