anti- RPRD1B antibody

Product Description

anti- RPRD1B antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Interacts with phosphorylated C-terminal heptapeptide repeat domain(CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation..

Immunogen: regulation of nuclear pre-mRNA domain containing 1B

Synonyms: C20orf77, CREPT

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07456( RPRD1B Antibody) at dilution of 1:1000

Gene ID: 58490

Research Area: Metabolism

Uniprot ID: Q9NQG5