Euro
British Pound
US Dollar
Product Description
anti- RSPO2 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6(LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors..
Immunogen: R-spondin 2 homolog
Synonyms: CRISTIN2, hRspo2, R spondin 2, Roof plate specific spondin 2, RSPO2
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IP
Recommended dilution: WB: 1:500-1:3000; IP: 1:500-1:1000
Image 1:
Image 2: .
Image 3:
Image 4: mouse brain tissue were subjected to SDS PAGE followed by western blot with FNab07511(RSPO2 antibody) at dilution of 1:1000
Gene ID: 340419
Research Area: Metabolism
Uniprot ID: Q6UXX9
