anti- SATB2 antibody

Product Description

anti- SATB2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Binds to DNA, at nuclear matrix-or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions(MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors(HDACs) or coactivators(HATs) directly to promoters and enhancers. Required for the initiation of the upper-layer neurons(UL1) specific genetic program and for the inactivation of deep-layer neurons(DL) and UL2 specific genes, probably by modulating BCL11B expression. Repressor of Ctip2 and regulatory determinant of corticocortical connections in the developing cerebral cortex. May play an important role in palate formation. Acts as a molecular node in a transcriptional network regulating skeletal development and osteoblast differentiation..

Immunogen: SATB homeobox 2

Synonyms: DNA binding protein SATB2, KIAA1034, SATB homeobox 2, SATB2

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB

Recommended dilution: WB: 1:500 - 1:2000

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Image 4: MCF7 cells were subjected to SDS PAGE followed by western blot with FNab07616(SATB2 antibody) at dilution of 1:1000

Gene ID: 23314

Research Area: Metabolism

Uniprot ID: Q9UPW6