anti- SETD1B antibody

Product Description

anti- SETD1B antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Histone methyltransferase that specifically methylates 'Lys-4' of histone H3, when part of the SET1 histone methyltransferase(HMT) complex, but not if the neighboring 'Lys-9' residue is already methylated. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. The non-overalpping localization with SETD1A suggests that SETD1A and SETD1B make non-redundant contributions to the epigenetic control of chromatin structure and gene expression. Specifically tri-methylates 'Lys-4' of histone H3 in vitro..

Immunogen: SET domain containing 1B

Synonyms: KIAA1076, KMT2G, SET1B

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IP, IHC,IF

Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:50-1:500

Image 1: Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using FNab07766(SETD1B Antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of ( 4% PFA) fixed MCF-7 cells using FNab07766 (SETD1B antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated Goat Anti-Rabbit IgG(H+L).

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07766(SETD1B antibody) at dilution of 1:1000

Gene ID: 23067

Research Area: Metabolism

Uniprot ID: Q9UPS6