anti- SF3B2 antibody

Product Description

anti- SF3B2 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus..

Immunogen: splicing factor 3b, subunit 2, 145kDa

Synonyms: SAP145

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded rat kidney using FNab07778(SF3B2 antibody) at dilution of 1:100

Image 2: .

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Image 4: HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07778(SF3B2 antibody) at dilution of 1:1000

Gene ID: 10992

Research Area: Metabolism

Uniprot ID: Q13435