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Product Description
anti- SF3B4 antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: Subunit of the splicing factor SF3B required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence(BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron..
Immunogen: splicing factor 3b, subunit 4, 49kDa
Synonyms: SAP49
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC
Recommended dilution:
Image 1: Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07780(SF3B4 antibody) at dilution of 1:50
Image 2: .
Image 3:
Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07780(SF3B4 antibody) at dilution of 1:500
Gene ID: 10262
Research Area: Metabolism
Uniprot ID: Q15427
