anti- SFPQ antibody

Product Description

anti- SFPQ antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: SFPQ, also named PSF, encodes a nuclear factor implicated in the splicing and regulation of gene expression. SFPQ probably forms a heteromer with NONO and participates in DNA pairing and DNA break repair program. Very recently SFPQ was identified as a downstream target of tau, complete nuclear depletion and cytoplasmic accumulation of SFPQ were shown in the neurons and astrocytes of brains with Alzheimer's disease (AD), more strikingly, reduced SFPQ levels may progress together with tau pathology, these observation strongly suggests the important role of SFPQ pathology in neurodegenerative diseases including AD. SFPQ protein may appears as 47 kDa, 52 kDa or 100 kDa molecules in various cell types. This antibody is a rabbit polyclonal antibody raised against the N-terminal of human SFPQ..

Immunogen: splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)

Synonyms: PSF

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC

Recommended dilution: WB: 1:500 - 1:1000; IHC: 1:50 - 1:200

Image 1: Immunohistochemistry of paraffin-embedded human stomach using FNab07785(SFPQ antibody) at dilution of 1:50

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07785(SFPQ antibody) at dilution of 1:1000

Gene ID: 6421

Research Area: Metabolism

Uniprot ID: P23246