anti- SH3PXD2A antibody

Product Description

anti- SH3PXD2A antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Adapter protein involved in invadopodia and podosome formation, extracellular matrix degradation and invasiveness of some cancer cells. Binds matrix metalloproteinases(ADAMs), NADPH oxidases(NOXs) and phosphoinositides. Acts as an organizer protein that allows NOX1-or NOX3-dependent reactive oxygen species(ROS) generation and ROS localization. In association with ADAM12, mediates the neurotoxic effect of beta-amyloid peptide..

Immunogen: SH3 and PX domains 2A

Synonyms: FISH, KIAA0418, SH3MD1, TKS5

Reactivity: Human, Mouse, Rat

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500-1:1000; IHC: 1:20-1:200; IF: 1:10-1:100

Image 1: Immunohistochemistry of paraffin-embedded human breast cancer using FNab07836(SH3PXD2A antibody) at dilution of 1:50

Image 2: Immunofluorescent analysis of HepG2 cells using FNab07836 (SH3PXD2A antibody) at dilution of 1:25 and Rhodamine-Goat anti-Rabbit IgG.

Image 3:

Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab07836(SH3PXD2A antibody) at dilution of 1:500

Gene ID: 9644

Research Area: Metabolism

Uniprot ID: Q5TCZ1