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Product Description
anti- SMN(Human, Mouse, Rat) antibody is available at Gentaur for Next week Delivery.
Purification: Protein A+G purification
Background: The survival of motor neurons(SMN) genes are the disease genes of spinal muscular atrophy(SMA), a common motor neuron degenerative disease. The level of SMN protein correlates with phenotypic severity of SMA. SMA patients lack a functional SMN1 gene, but they possess an intact SMN2 gene, which though nearly identical to SMN1, is only partially functional, because a large majority of SMN2 transcripts lack exon 7, resulting in production of a truncated, less stable SMN protein. This antibody can recognize human,mouse and rat SMN..
Immunogen: survival of motor neuron 2, centromeric
Synonyms: C BCD541, Component of gems 1, FLJ76644, Gemin 1, SMN, SMN1, SMN1,SMN, SMN2, SMNC, SMNT, Survival motor neuron protein
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB
Recommended dilution: WB: 1:1000-1:6000; IF: 1:50-1:500
Image 1:
Image 2: Immunofluorescent analysis of ( -20? Ethanol) fixed HEK-293 cells using FNab08033 (SMN antibody) at dilution of 1:100 and Alexa Fluor 488-congugated Goat Anti-Mouse IgG(H+L).
Image 3:
Image 4: A375 cells were subjected to SDS PAGE followed by western blot with FNab08033(SMN antibody) at dilution of 1:3000
Research Area: Metabolism
Uniprot ID: Q16637
