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Product Description
anti- SQLE antibody is available at Gentaur for Next week Delivery.
Purification: Immunogen affinity purified
Background: SQLE, also named as ERG1, SE and SM, belongs to the squalene monooxygenase family. It catalyzes the first oxygenation step in cholesterol synthesis, acting on squalene before cyclization into the basic steroid structure. SQLE may serve as a flux-controlling enzyme beyond 3-hydroxy-3-methylglutaryl-coenzyme A reductase(HMGR, considered as rate limiting). It is also posttranslationally regulated by cholesterol-dependent proteasomal degradation.(PMID:21356516) The MW of SQLE is about 64kd..
Immunogen: squalene epoxidase
Synonyms: ERG1, FLJ30795, SE, SM, SQLE, squalene epoxidase, Squalene monooxygenase
Reactivity: Human, Mouse, Rat
Tested Application: ELISA, WB, IHC, IP, IF
Recommended dilution: WB: 1:200-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Image 1: Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08209(SQLE Antibody) at dilution of 1:50
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Image 4: A549 cells were subjected to SDS PAGE followed by western blot with FNab08209(SQLE antibody) at dilution of 1:300
Gene ID: 6713
Research Area: Metabolism
Uniprot ID: Q14534
