anti- SRY antibody

Product Description

anti- SRY antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors(pre-Sertoli cells) as Sertoli rather than granulosa cells(By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons(By similarity). Involved in different aspects of gene regulation including promoter activation or repression(By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'..

Immunogen: sex determining region Y

Synonyms: TDF

Reactivity: Human

Tested Application: ELISA, WB

Recommended dilution:

Image 1: Immunohistochemistry of paraffin-embedded human kidney using FNab08244(SRY antibody) at dilution of 1:100

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Image 4: human testis tissue were subjected to SDS PAGE followed by western blot with FNab08244(SRY antibody) at dilution of 1:500

Gene ID: 6736

Research Area: Metabolism

Uniprot ID: Q05066