anti- SSRP1 antibody

Product Description

anti- SSRP1 antibody is available at Gentaur for Next week Delivery.

Purification: Immunogen affinity purified

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known..

Immunogen: structure specific recognition protein 1

Synonyms: FACT80

Reactivity: Human, Mouse

Tested Application: ELISA, WB, IHC, IF

Recommended dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:10 - 1:100

Image 1: Immunohistochemistry of paraffin-embedded mouse liver using FNab08250(SSRP1 antibody) at dilution of 1:100

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Image 4: HeLa cells were subjected to SDS PAGE followed by western blot with FNab08250(SSRP1 antibody) at dilution of 1:1000

Gene ID: 6749

Research Area: Metabolism

Uniprot ID: Q08945